Gene

lin28a

ID
ZDB-GENE-040426-747
Name
lin-28 homolog A (C. elegans)
Symbol
lin28a Nomenclature History
Previous Names
  • lin28
  • sb:cb650
  • zgc:55584 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and polysome binding activity. Involved in chordate embryonic development; negative regulation of gene expression; and regeneration. Predicted to localize to cytoplasmic ribonucleoprotein granule; nucleus; and polysome. Is expressed in several structures, including Kupffer's vesicle; central nervous system; digestive system; neural plate; and neural tube. Orthologous to human LIN28A (lin-28 homolog A).
Genome Resources
Note
None
Expression
All Expression Data
22 figures from 9 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lin28a Human Ortholog
No data available
Associated With lin28a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001878 Zinc finger, CCHC-type
Domain IPR002059 Cold-shock protein, DNA-binding
Domain IPR011129 Cold shock domain
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR036875 Zinc finger, CCHC-type superfamily
Domain Details Per Protein
Protein Length Cold shock domain Cold-shock protein, DNA-binding Nucleic acid-binding, OB-fold Zinc finger, CCHC-type Zinc finger, CCHC-type superfamily
UniProtKB:I3IS11 194
UniProtKB:A0A2R8Q8W5 207
UniProtKB:A5PMB5 102
UniProtKB:I3ITG7 59
UniProtKB:Z4YIC2 179
UniProtKB:Q803L0 202
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations