Gene
lin28ab
- ID
- ZDB-GENE-040426-747
- Name
- lin-28 homolog Ab
- Symbol
- lin28ab Nomenclature History
- Previous Names
-
- lin28
- lin28a
- sb:cb650
- zgc:55584 (1)
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Is predicted to enable RNA binding activity and polysome binding activity. Involved in RNA metabolic process; positive regulation of cytoplasmic translation; and stem cell population maintenance. Acts upstream of or within chordate embryonic development; negative regulation of gene expression; and regeneration. Predicted to be located in P-body; cytoplasmic stress granule; and nucleus. Predicted to be part of polysome. Is expressed in several structures, including Kupffer's vesicle; central nervous system; digestive system; neural plate; and neural tube. Orthologous to human LIN28A (lin-28 homolog A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb650 (33 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cold shock domain | Cold-shock protein, DNA-binding | Nucleic acid-binding, OB-fold | Zinc finger, CCHC-type | Zinc finger, CCHC-type superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q803L0
|
202 | |||||
|
UniProtKB:A0A2R8Q8W5
|
207 | |||||
|
UniProtKB:I3IS11
|
194 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
lin28a-001
(1)
|
2020 nt | |
| mRNA |
lin28a-202
(1)
|
494 nt | |
| mRNA |
lin28a-203
(1)
|
607 nt | |
| mRNA |
lin28a-204
(1)
|
547 nt | |
| mRNA |
lin28a-206
(1)
|
908 nt | |
| ncRNA |
lin28a-005
(1)
|
793 nt |
Interactions and Pathways
No data available
Plasmids