Gene

ncapd3

ID

ZDB-GENE-040426-737

Name

non-SMC condensin II complex, subunit D3

Symbol

ncapd3 Nomenclature History

Previous Names

id:ibd2253
zgc:55549 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have chromatin binding activity and histone binding activity. Predicted to be involved in chromosome separation; meiotic chromosome condensation; and mitotic chromosome condensation. Predicted to localize to condensed chromosome, centromeric region and nuclear condensin complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD3 (non-SMC condensin II complex subunit D3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ncapd3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Microcephaly 22, primary, autosomal recessive	617984

Associated With ncapd3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR032682	Condensin complex subunit 1, C-terminal
Family	IPR012371	Condensin-2 complex subunit D3
Family	IPR026971	Condensin subunit 1/Condensin-2 complex subunit D3
Homologous_superfamily	IPR011989	Armadillo-like helical
Homologous_superfamily	IPR016024	Armadillo-type fold