ZFIN ID: ZDB-GENE-040426-731
Gene Name: bromodomain and PHD finger containing, 1
Gene Symbol: brpf1    Nomenclature History

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Previous Name: zgc:55530 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Exhibits histone binding activity. Involved in anterior/posterior pattern specification. Localizes to the nuclear chromatin. Is expressed in brain; digestive system; epithelium; head; and olfactory pit. Orthologous to human BRPF1 (bromodomain and PHD finger containing 1).
Genome Resources: Alliance (1),  Gene:393991 (1),  Ensembl(GRCz11):ENSDARG00000103665 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b943 Point Mutation Unknown Unknown ENU
sa24810 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39525 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t20002 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • t25114 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-brpf1 N/A 1
    MO2-brpf1 N/A 1
    DISEASE ASSOCIATED WITH brpf1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Intellectual developmental disorder with dysmorphic facies and ptosis 617333
    DISEASE ASSOCIATED WITH brpf1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior pattern specification (more)
    Cellular Component nuclear chromatin (more)
    Molecular Function histone binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000313 PWWP domain
    Domain IPR001487 Bromodomain
    Domain IPR001965 Zinc finger, PHD-type
    Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Domain IPR013087 Zinc finger C2H2-type
    Conserved_site IPR018359 Bromodomain, conserved site
    Domain IPR019542 Enhancer of polycomb-like, N-terminal
    Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
    Domain IPR019787 Zinc finger, PHD-finger
    Domain IPR034732 Extended PHD (ePHD) domain
    Domain IPR035502 BR140-related, PWWD domain
    Homologous_superfamily IPR036427 Bromodomain-like superfamily
    Domain IPR042008 BRPF1, PHD domain
    Domain IPR042061 Peregrin, ePHD domain
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM brpf1 No data available
    MARKER RELATIONSHIPS
    brpf1 Encodes: [cDNA] MGC:55530 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201016 (1) 3164 bp
    Genomic GenBank:CABZ01085599 (1) 4098 bp
    Polypeptide UniProtKB:A0A0G2L9X9 (1) 1259 aa
    Sequence Information (all 18)
    ORTHOLOGY for brpf1 ( Chr: 8 )
    CITATIONS (26)