ZFIN ID: ZDB-GENE-040426-721
Gene Name: mannosidase, beta A, lysosomal
Gene Symbol: manba    Nomenclature History

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Previous Names: zgc:55493 (1), zgc:76896

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have beta-mannosidase activity. Predicted to be involved in glycoprotein catabolic process. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in beta-mannosidosis. Orthologous to human MANBA (mannosidase beta).
Genome Resources: Alliance (1),  Gene:393128 (1),  Ensembl(GRCz11):ENSDARG00000008238 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55493]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-manba N/A 1
PHENOTYPE
Data: 2 figures from Ko et al., 2017
Observed in:
DISEASE ASSOCIATED WITH manba HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
beta-mannosidosis Alliance Mannosidosis, beta 248510
DISEASE ASSOCIATED WITH manba VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process carbohydrate metabolic process (more)
Cellular Component lysosome (more)
Molecular Function hydrolase activity, hydrolyzing O-glycosyl compounds (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM manba No data available
MARKER RELATIONSHIPS
manba Contained in: [BAC] CH211-195E19 (1), CH211-264D7 (1), DKEY-261G4 (1) (order this)
manba Encodes: [cDNA] MGC:55493 (1), MGC:76896 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_200159 (1) 2999 nt
Genomic GenBank:CR559945 (1) 186151 nt
Select Tool
Polypeptide UniProtKB:A0A2R8Q808 (1) 934 aa
Sequence Information (all 16)
ORTHOLOGY for manba ( Chr: 13 )
CITATIONS (19)