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ZIRC
ZFIN ID: ZDB-GENE-040426-720
Gene Name: negative elongation factor complex member C/D
Gene Symbol: nelfcd    Nomenclature History

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Previous Names: th1l, zgc:55482 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have RNA binding activity. Predicted to be involved in negative regulation of transcription elongation from RNA polymerase II promoter. Predicted to localize to the NELF complex. Orthologous to human NELFCD (negative elongation factor complex member C/D).
Genome Resources: Alliance (1),  Gene:394165 (1),  Ensembl(GRCz11):ENSDARG00000021097 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55482]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20815 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nelfcd HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH nelfcd VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of transcription, DNA-templated (more)
    Cellular Component nucleus (more)
    Molecular Function RNA binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006942 (1)
  • Pfam:PF04858 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nelfcd-201 (1)    Ensembl 2553
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nelfcd No data available
    MARKER RELATIONSHIPS
    nelfcd Contained in: [BAC] CH211-122I22 (1) (order this)
    nelfcd Encodes: [cDNA] MGC:55482 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201190 (1) 2024 bp
    Genomic GenBank:BX927257 (1) 133388 bp
    Select Tool
    Polypeptide UniProtKB:F1Q889 (1) 579 aa
    Sequence Clusters UniGene:115420 (1)
    Sequence Information (all 10)
    ORTHOLOGY for nelfcd ( Chr: 6 )
    CITATIONS (19)