ZFIN ID: ZDB-GENE-040426-708
Gene Name: transportin 3
Gene Symbol: tnpo3    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:55409 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Involved in RNA splicing; T cell differentiation; and mRNA processing. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in autosomal dominant limb-girdle muscular dystrophy type 2. Orthologous to human TNPO3 (transportin 3).
Genome Resources: Alliance (1),  Gene:394062 (1),  Ensembl(GRCz11):ENSDARG00000045680 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55409]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8594 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13543 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20237 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44585 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • t22074 Point Mutation Unknown Premature Stop ENU
    DISEASE ASSOCIATED WITH tnpo3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant limb-girdle muscular dystrophy type 2 Alliance Muscular dystrophy, limb-girdle, autosomal dominant 2 608423
    DISEASE ASSOCIATED WITH tnpo3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process T cell differentiation (more)
    Cellular Component nucleus (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tnpo3-202 (1)    Ensembl 3793
    ncRNA tnpo3-002 (1)    Ensembl 805
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tnpo3 No data available
    MARKER RELATIONSHIPS
    tnpo3 Contained in: [BAC] CH211-266A5 (1)
    tnpo3 Encodes: [cDNA] MGC:55409 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201087 (1) 3833 nt
    Genomic GenBank:BX465210 (1) 171708 nt
    Select Tool
    Polypeptide UniProtKB:Q7ZW13 (1) 923 aa
    Sequence Information (all 10)
    ORTHOLOGY for tnpo3 ( Chr: 4 )
    CITATIONS (22)