Gene

crkl

ID
ZDB-GENE-040426-2951
Name
v-crk avian sarcoma virus CT10 oncogene homolog-like
Symbol
crkl Nomenclature History
Previous Names
  • wu:fa55g05
  • wu:fj60e01
  • zgc:63469 (1)
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Involved in myoblast fusion and pronephros morphogenesis. Human ortholog(s) of this gene implicated in chronic myeloid leukemia. Is expressed in pronephros. Orthologous to human CRKL (CRK like proto-oncogene, adaptor protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With crkl Human Ortholog
No data available
Associated With crkl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001452 SH3 domain
Domain IPR035457 CRK, N-terminal SH3 domain
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length CRK, N-terminal SH3 domain SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily
UniProtKB:Q6PH06 305
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations