ZFIN ID: ZDB-GENE-040426-2951
Gene Name: v-crk avian sarcoma virus CT10 oncogene homolog-like
Gene Symbol: crkl    Nomenclature History

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Previous Names: wu:fa55g05, wu:fj60e01, zgc:63469 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Involved in myoblast fusion and pronephros morphogenesis. Is expressed in pronephros. Human ortholog(s) of this gene implicated in chronic myeloid leukemia. Orthologous to human CRKL (CRK like proto-oncogene, adaptor protein).
Genome Resources: Alliance (1),  Gene:556443 (1),  Ensembl(GRCz11):ENSDARG00000028699 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63469]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-crkl
1
MO1-crkl N/A 2
MO2-crkl N/A 1
DISEASE ASSOCIATED WITH crkl HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH crkl VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process myoblast fusion (more)
Cellular Component cellular_component (more)
GO Terms (all 3)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA crkl-201 (1)    Ensembl 2780
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM crkl No data available
MARKER RELATIONSHIPS
crkl Contained in: [BAC] CH211-222N4 (1)
crkl Encodes: [EST] fa55g05 (1), fi03a08 (1), fj60e01 (1)
[cDNA] MGC:63469 (1), MGC:198125 (1), MGC:198127 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213538 (1) 2807 nt
Genomic GenBank:CU467622 (1) 128877 nt
Select Tool
Polypeptide UniProtKB:Q6PH06 (1) 305 aa
Sequence Information (all 19)
ORTHOLOGY for crkl ( Chr: 21 )
CITATIONS (23)