ZFIN ID: ZDB-GENE-040426-2931
Gene Name: keratin 15
Gene Symbol: krt15    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wu:fa91c06, wu:fa95d04, zgc:55334

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have structural molecule activity. Predicted to localize to intermediate filament. Is expressed in cloaca; lateral line system; neuromast mantle cell; and pharyngeal arch 3-7 skeleton. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive woolly hair 3; corneal dystrophy (multiple); ectodermal dysplasia (multiple); epidermolysis bullosa simplex (multiple); and palmoplantar keratosis (multiple). Orthologous to several human genes including KRT15 (keratin 15).
Genome Resources: Alliance (1),  Gene:406844 (1),  Ensembl(GRCz11):ENSDARG00000036840 (1)
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [MGC:55334]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011923Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017658Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027220Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la027221Tg Transgenic Insertion Unknown Unknown DNA
    sa6196 Point Mutation Unknown Premature Stop ENU
    sa35039 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35040 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-krt15
    2
    CRISPR2-krt15
    4
    CRISPR3-krt15
    2
    CRISPR4-krt15
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH krt15 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH krt15 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biological_process (more)
    Cellular Component intermediate filament (more)
    Molecular Function structural molecule activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA krt15-201 (1)    Ensembl 1545
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM krt15 No data available
    MARKER RELATIONSHIPS
    krt15 Contained in: [BAC] DKEY-28E7 (1) (order this)
    krt15 Encodes: [EST] fa91c06, fa95d04
    [cDNA] MGC:55334 (1), MGC:191718 (1)
    krt15 Has Artifact: [cDNA] MGC:92147
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213523 (1) 1553 nt
    Genomic GenBank:CR556712 (1) 112718 nt
    Select Tool
    Polypeptide UniProtKB:Q803Y5 (1) 463 aa
    Sequence Information (all 21)
    ORTHOLOGY for krt15 ( Chr: 11 )
    CITATIONS (36)