ZFIN ID: ZDB-GENE-040426-2922
Gene Name: charged multivesicular body protein 2A
Gene Symbol: chmp2a    Nomenclature History

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Previous Names: bc2 (1), fj10d05 (1), wu:fi18h03, wu:fj10d05 (1), zgc:55361 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to be involved in several processes, including endosome transport via multivesicular body sorting pathway; exit from mitosis; and late endosome to vacuole transport. Predicted to localize to ESCRT III complex; multivesicular body; and nuclear envelope. Orthologous to human CHMP2A (charged multivesicular body protein 2A).
Genome Resources: Alliance (1),  Gene:798901 (1),  Ensembl(GRCz11):ENSDARG00000053979 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55361]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7136173]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:7139900]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi3512bTg Transgenic Insertion Donor Splice Site of Exon 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa4469 Point Mutation Unknown Splice Site ENU
    sa8643 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22108 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH chmp2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH chmp2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process exit from mitosis (more)
    Cellular Component nuclear envelope (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chmp2a-201 (1)    Ensembl 1682
    ncRNA bc2-003 (1)    Ensembl 530
    bc2-004 (1)    Ensembl 757
    bc2-005 (1)    Ensembl 757
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chmp2a No data available
    MARKER RELATIONSHIPS
    chmp2a Contained in: [BAC] DKEY-245I6 (1) (order this)
    chmp2a Encodes: [EST] fi18h03 (1), fj10d05, IMAGE:7136173 (1), IMAGE:7139900 (1)
    [cDNA] MGC:55361 (1), MGC:174106 (1), MGC:198141 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213517 (1) 1712 nt
    Genomic GenBank:AL929039 (1) 162385 nt
    Select Tool
    Polypeptide UniProtKB:A7MCL9 (1) 220 aa
    Sequence Information (all 23)
    ORTHOLOGY for chmp2a ( Chr: 12 )
    CITATIONS (34)