ZFIN ID: ZDB-GENE-040426-2850
Gene Name: mediator complex subunit 25
Gene Symbol: med25    Nomenclature History

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Previous Name: zgc:63555

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Involved in roof of mouth development. Predicted to localize to mediator complex and transcription regulator complex. Is expressed in head; post-vent region; and trunk. Orthologous to several human genes including MED25 (mediator complex subunit 25).
Genome Resources: Alliance (1),  Gene:406793 (1),  Ensembl(GRCz11):ENSDARG00000038005 (1)
GENE EXPRESSION
All Expression Data: Fig. 4 from Nakamura et al., 2011
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024095Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33195 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-med25 N/A 2
    MO2-med25 N/A 1
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH med25 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Basel-Vanagait-Smirin-Yosef syndrome 616449
    DISEASE ASSOCIATED WITH med25 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process roof of mouth development (more)
    Cellular Component nucleus (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript med25-202 (1)    Ensembl 1954
    mRNA med25-201 (1)    Ensembl 2722
    med25-203 (1)    Ensembl 730
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM med25 No data available
    MARKER RELATIONSHIPS
    med25 Contained in: [BAC] DKEY-13N23 (1) (order this)
    med25 Encodes: [cDNA] MGC:63555 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_214766 (1) 2737 nt
    Genomic GenBank:CR936968 (1) 207843 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4ISF9 (1) 729 aa
    Sequence Information (all 24)
    ORTHOLOGY for med25 ( Chr: 3 )
    CITATIONS (25)