Gene

med25

ID
ZDB-GENE-040426-2850
Name
mediator complex subunit 25
Symbol
med25 Nomenclature History
Previous Names
  • zgc:63555
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within roof of mouth development. Predicted to be located in nucleus. Predicted to be part of mediator complex and transcription regulator complex. Is expressed in head; post-vent region; and trunk. Orthologous to several human genes including MED25 (mediator complex subunit 25).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Nakamura et al., 2011
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With med25 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Basel-Vanagait-Smirin-Yosef syndrome 616449
Associated With med25 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002035 von Willebrand factor, type A
Domain IPR021394 Mediator complex, subunit Med25, PTOV domain
Domain IPR021406 Mediator complex, subunit Med25, NR box
Family IPR021419 Mediator complex, subunit Med25, von Willebrand factor type A
Homologous_superfamily IPR036465 von Willebrand factor A-like domain superfamily
Homologous_superfamily IPR038196 PTOV domain superfamily
Domain Details Per Protein
Protein Length Mediator complex, subunit Med25, NR box Mediator complex, subunit Med25, PTOV domain Mediator complex, subunit Med25, von Willebrand factor type A PTOV domain superfamily von Willebrand factor A-like domain superfamily von Willebrand factor, type A
UniProtKB:I3ITN5 172
UniProtKB:Q6PEH8 701
UniProtKB:A0A0R4ISF9 729
UniProtKB:A0A2R8Q3L3 705
UniProtKB:F1R0J2 701
UniProtKB:I3IRZ0 149
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations