ZFIN ID: ZDB-GENE-040426-2836
Gene Name: upf1 regulator of nonsense transcripts homolog (yeast)
Gene Symbol: upf1
Previous Names: rent1, wu:fi40f07, wu:fj48a01, zgc:55472 (1)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55472]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
la028839Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11856 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-upf1 (2), MO1-upf1 (1), MO2-upf1 (1)
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in: brain, central nervous system, embryo development, extension (all 8) expand
    DISEASE ASSOCIATED WITH upf1 HUMAN ORTHOLOG No data available
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR018999 (1)
  • InterPro:IPR027417 (1)
  • Pfam:PF09416 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA upf1-001 (1) 3260
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM upf1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    upf1Contained in: [BAC] CH211-59P9 (1) (order this), DKEY-251J8 (1) (order this)
    upf1Encodes: [EST] fi40f07 (1), fj48a01 (1)
    [cDNA] MGC:55472 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213474 (1) 3920bp
    Genomic GenBank:CU693375 (1) 195548bp
    Select Tool
    Polypeptide UniProtKB:F1RCY6 (1) 1100aa
    Sequence Clusters UniGene:96025 (1)
    Sequence Information (all 19)
    OTHER upf1 GENE PAGES 
  • Gene:406783 (1)
  • VEGA:OTTDARG00000023966 (1)
  • Ensembl(GRCz10):ENSDARG00000016302 (1)
  • ORTHOLOGY for upf1 (Chr: 2) 
    Species Symbol Chromosome Accession # Evidence
    Human UPF1 19
  • Gene:5976
  • OMIM:601430
  • HGNC:9962
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Upf1 8
  • MGI:107995
  • Gene:19704
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (24)