Gene

upf1

ID
ZDB-GENE-040426-2836
Name
UPF1 RNA helicase and ATPase
Symbol
upf1 Nomenclature History
Previous Names
  • rent1
  • wu:fi40f07
  • wu:fj48a01
  • zgc:55472 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have RNA binding activity and RNA helicase activity. Involved in chordate embryonic development and nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to localize to cytoplasm. Orthologous to human UPF1 (UPF1 RNA helicase and ATPase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With upf1 Human Ortholog
No data available
Associated With upf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006935 Helicase/UvrB, N-terminal
Domain IPR018999 RNA helicase UPF1, Cys/His rich zinc-binding domain
Domain IPR040812 RNA helicase UPF1, 1B domain
Domain IPR041677 DNA2/NAM7 helicase, helicase domain
Domain IPR041679 DNA2/NAM7 helicase-like, C-terminal
Domain IPR047187 Upf1-like, C-terminal helicase domain
Family IPR045055 DNA2/NAM7-like helicase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length DNA2/NAM7 helicase, helicase domain DNA2/NAM7 helicase-like, C-terminal DNA2/NAM7-like helicase Helicase/UvrB, N-terminal P-loop containing nucleoside triphosphate hydrolase RNA helicase UPF1, 1B domain RNA helicase UPF1, Cys/His rich zinc-binding domain Upf1-like, C-terminal helicase domain
UniProtKB:Q7ZVZ4 1100
UniProtKB:F1RCY6 1100
UniProtKB:A0A8I7ZFH8
UniProtKB:A0A8M2BAV2 1099
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA upf1-201 (1) Ensembl 8456 nt
mRNA upf1-202 (1) Havana 3260 nt
mRNA upf1-203 (1) Ensembl 8615 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations