ZFIN ID: ZDB-GENE-040426-2828
Gene Name: exonuclease 1
Gene Symbol: exo1    Nomenclature History

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Previous Names: fc16e04 (1), wu:fc16e04 (1), zgc:55521 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have 5'-flap endonuclease activity and single-stranded DNA 5'-3' exodeoxyribonuclease activity. Predicted to be involved in DNA recombination and mismatch repair. Predicted to localize to nucleus. Is expressed in proliferative region. Orthologous to human EXO1 (exonuclease 1).
Genome Resources: Alliance (1),  Gene:406778 (1),  Ensembl(GRCz11):ENSDARG00000056832 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [IMAGE:7149750]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17356 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42919 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH exo1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH exo1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process DNA recombination (more)
    Cellular Component nucleus (more)
    Molecular Function flap endonuclease activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA exo1-201 (1)    Ensembl 2735
    exo1-202 (1)    Ensembl 547
    exo1-203 (1)    Ensembl 811
    ncRNA exo1-004 (1)    Ensembl 608
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM exo1 No data available
    MARKER RELATIONSHIPS
    exo1 Contained in: [BAC] CH211-125O16 (1)
    exo1 Encodes: [EST] fc16e04, IMAGE:7149750 (1)
    [cDNA] MGC:55521 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213469 (1) 2686 nt
    Genomic GenBank:BX511245 (1) 96687 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QI59 (1) 806 aa
    Sequence Information (all 17)
    ORTHOLOGY for exo1 ( Chr: 17 )
    CITATIONS (22)