Gene

pgd

ID
ZDB-GENE-040426-2807
Name
phosphogluconate dehydrogenase
Symbol
pgd Nomenclature History
Previous Names
  • fi03d03 (1)
  • wu:fi03d03 (1)
  • zgc:111848
  • zgc:55585 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Is predicted to enable NADP binding activity and phosphogluconate dehydrogenase (decarboxylating) activity. Involved in D-gluconate catabolic process and pentose-phosphate shunt, oxidative branch. Acts upstream of or within D-gluconate metabolic process and pentose-phosphate shunt. Is expressed in several structures, including axis; chordo neural hinge; digestive system; sensory system; and solid lens vesicle. Orthologous to human PGD (phosphogluconate dehydrogenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pgd Human Ortholog
No data available
Associated With pgd Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR006184 6-phosphogluconate-binding site
Domain IPR006114 6-phosphogluconate dehydrogenase, C-terminal
Domain IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
Family IPR006113 6-phosphogluconate dehydrogenase, decarboxylating
Family IPR006183 6-phosphogluconate dehydrogenase
Homologous_superfamily IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Homologous_superfamily IPR013328 6-phosphogluconate dehydrogenase, domain 2
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 6-phosphogluconate-binding site 6-phosphogluconate dehydrogenase 6-phosphogluconate dehydrogenase, C-terminal 6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconate dehydrogenase, domain 2 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 6-phosphogluconate dehydrogenase, NADP-binding NAD(P)-binding domain superfamily
UniProtKB:Q803T9 511
UniProtKB:Q502S9 483
UniProtKB:Q6TNR8 483
UniProtKB:F1Q883 511
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations