ZFIN ID: ZDB-GENE-040426-2787
Gene Name: pleiotropic regulator 1
Gene Symbol: plrg1
Sequence Ontology ID : SO:0000704

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Previous Names: wu:fi74f01, zgc:55651, zgc:86603

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in negative regulation of DNA damage response, signal transduction by p53 class mediator and negative regulation of apoptotic process; predicted to colocalize with the DNA replication factor  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7138004]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1902Tg Transgenic Insertion Unknown Unknown DNA
hi3174aTg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13503 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24845 Point Mutation Unknown Premature Stop ENU
    sa38266 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko487a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • zko487b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 6 figures from 5 publications
    Observed in:
    DISEASE ASSOCIATED WITH plrg1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH plrg1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of DNA damage response, signal transduction by p53 class mediator (more)
    Cellular Component catalytic step 2 spliceosome (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001680 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • InterPro:IPR020472 (1)
  • InterPro:IPR036322 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF00400 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA plrg1-201 (1) 2192
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM plrg1 No data available
    MARKER RELATIONSHIPS
    plrg1Contained in: [BAC] DKEY-30K22 (1) (order this)
    plrg1Encodes: [EST] fi74f01 (1), IMAGE:7138004 (1) (order this)
    [cDNA] MGC:55651 (1) (order this), MGC:86603 (1) (order this), MGC:174842 (1) (order this), MGC:191623 (1), MGC:198378 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213440 (1) 2163bp
    Genomic GenBank:AL935184 (1) 255909bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q5U3B5 (1) 511aa
    Sequence Clusters UniGene:79159 (1)
    Sequence Information (all 37)
    OTHER plrg1 GENE PAGES
  • Alliance (1)
  • Gene:100004402 (1)
  • VEGA:OTTDARG00000021733 (1)
  • ORTHOLOGY for plrg1 (Chr: 1)
    CITATIONS (25)