Gene

plrg1

ID
ZDB-GENE-040426-2787
Name
pleiotropic regulator 1
Symbol
plrg1 Nomenclature History
Previous Names
  • wu:fi74f01
  • zgc:55651
  • zgc:86603
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Acts upstream of or within negative regulation of DNA damage response, signal transduction by p53 class mediator and negative regulation of apoptotic process. Predicted to be part of Prp19 complex and catalytic step 2 spliceosome. Orthologous to human PLRG1 (pleiotropic regulator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With plrg1 Human Ortholog
No data available
Associated With plrg1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Family IPR045241 WD repeat Prp46/PLRG1-like
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein beta WD-40 repeat WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily WD repeat Prp46/PLRG1-like
UniProtKB:Q6TNR7 510
UniProtKB:B5DDG5 266
UniProtKB:E7F399 252
UniProtKB:F1QSZ2 505
UniProtKB:Q6DRE2 511
UniProtKB:Q5U3B5 511
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations