Gene

fpgs

ID
ZDB-GENE-040426-2781
Name
folylpolyglutamate synthase
Symbol
fpgs Nomenclature History
Previous Names
  • fk51d09
  • wu:fk49h03
  • wu:fk51d09
  • zgc:63807
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have tetrahydrofolylpolyglutamate synthase activity. Predicted to be involved in tetrahydrofolylpolyglutamate biosynthetic process. Predicted to localize to cytosol and mitochondrion. Is expressed in several structures, including alar plate midbrain region; liver; nervous system; optic vesicle; and yolk syncytial layer. Orthologous to human FPGS (folylpolyglutamate synthase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fpgs Human Ortholog
No data available
Associated With fpgs Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018109 Folylpolyglutamate synthetase, conserved site
Family IPR001645 Folylpolyglutamate synthetase
Family IPR023600 Folylpolyglutamate synthase, eukaryota
Homologous_superfamily IPR036565 Mur-like, catalytic domain superfamily
Homologous_superfamily IPR036615 Mur ligase, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Folylpolyglutamate synthase, eukaryota Folylpolyglutamate synthetase Folylpolyglutamate synthetase, conserved site Mur ligase, C-terminal domain superfamily Mur-like, catalytic domain superfamily
UniProtKB:A0A2R8RY36 562
UniProtKB:F1Q7N0 572
UniProtKB:Q6PE17 572
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations