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Gene

e2f4

ID
ZDB-GENE-040426-2773
Name
E2F transcription factor 4
Symbol
e2f4 Nomenclature History
Previous Names
  • fb72f07
  • wu:fb72f07 (1)
  • wu:fe05f06
  • zgc:63815
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within mitotic cell cycle and regulation of transcription, DNA-templated. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in adenohypophysis; head; and trunk. Orthologous to human E2F4 (E2F transcription factor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Xie et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With e2f4 Human Ortholog
No data available
Associated With e2f4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003316 E2F/DP family, winged-helix DNA-binding domain
Domain IPR032198 E2F transcription factor, CC-MB domain
Family IPR015633 E2F Family
Family IPR028312 Transcription factor E2F4
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Homologous_superfamily IPR037241 E2F-DP heterodimerization region
Domain Details Per Protein
Protein Length E2F/DP family, winged-helix DNA-binding domain E2F-DP heterodimerization region E2F Family E2F transcription factor, CC-MB domain Transcription factor E2F4 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A0R4ICD5 404
UniProtKB:A0A2R8QLN2 392
UniProtKB:A0A2R8Q893 389
UniProtKB:Q6PGU1 393
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations