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ZIRC
ZFIN ID: ZDB-GENE-040426-2763
Gene Name: mediator complex subunit 21
Gene Symbol: med21    Nomenclature History

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Previous Names: fk48d02, surb7 (1), wu:fk48d02, zgc:56532 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to the mediator complex. Orthologous to human MED21 (mediator complex subunit 21).
Genome Resources: Alliance (1),  Gene:406732 (1),  Ensembl(GRCz11):ENSDARG00000026839 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56532]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20175 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH med21 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH med21 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of transcription by RNA polymerase II (more)
    Cellular Component mediator complex (more)
    Molecular Function transcription coregulator activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR021384 (1)
  • InterPro:IPR037212 (1)
  • Pfam:PF11221 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA med21-201 (1)    Ensembl 823
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM med21 No data available
    MARKER RELATIONSHIPS
    med21 Contained in: [BAC] CH211-203H15 (1) (order this)
    med21 Encodes: [EST] fk48d02
    [cDNA] MGC:56532 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213423 (1) 807 bp
    Genomic GenBank:CR847994 (1) 100991 bp
    Select Tool
    Polypeptide UniProtKB:Q7ZTI5 (1) 145 aa
    Sequence Clusters UniGene:81879 (1)
    Sequence Information (all 12)
    ORTHOLOGY for med21 ( Chr: 4 )
    CITATIONS (24)