Gene
pgk1
- ID
- ZDB-GENE-040426-2711
- Name
- phosphoglycerate kinase 1
- Symbol
- pgk1 Nomenclature History
- Previous Names
-
- wu:fd59b07
- wu:fj36g06
- zgc:56252
- zgc:77899
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Involved in positive regulation of oxidative phosphorylation and response to hypoxia. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in hemolytic anemia. Is expressed in liver and olfactory bulb. Orthologous to human PGK1 (phosphoglycerate kinase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| phosphoglycerate kinase 1 deficiency | Alliance | Phosphoglycerate kinase 1 deficiency | 300653 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Phosphoglycerate kinase | Phosphoglycerate kinase, conserved site | Phosphoglycerate kinase, N-terminal | Phosphoglycerate kinase superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q7ZV29
|
417 |
Interactions and Pathways
No data available
Plasmids
No data available