Gene

pgk1

ID
ZDB-GENE-040426-2711
Name
phosphoglycerate kinase 1
Symbol
pgk1 Nomenclature History
Previous Names
  • wu:fd59b07
  • wu:fj36g06
  • zgc:56252
  • zgc:77899
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Involved in positive regulation of oxidative phosphorylation and response to hypoxia. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in hemolytic anemia. Is expressed in liver and olfactory bulb. Orthologous to human PGK1 (phosphoglycerate kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pgk1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
phosphoglycerate kinase 1 deficiency Alliance Phosphoglycerate kinase 1 deficiency 300653
Associated With pgk1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR015911 Phosphoglycerate kinase, conserved site
Family IPR001576 Phosphoglycerate kinase
Homologous_superfamily IPR015824 Phosphoglycerate kinase, N-terminal
Homologous_superfamily IPR036043 Phosphoglycerate kinase superfamily
Domain Details Per Protein
Protein Length Phosphoglycerate kinase Phosphoglycerate kinase, conserved site Phosphoglycerate kinase, N-terminal Phosphoglycerate kinase superfamily
UniProtKB:Q6P003 417
UniProtKB:Q7ZV29 417
UniProtKB:F1QXV8 417
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations