ZFIN ID: ZDB-GENE-040426-2711
Gene Name: phosphoglycerate kinase 1
Gene Symbol: pgk1    Nomenclature History

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Previous Names: wu:fd59b07, wu:fj36g06, zgc:56252, zgc:77899

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to have ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Involved in positive regulation of oxidative phosphorylation and response to hypoxia. Predicted to localize to cytosol. Is expressed in liver and olfactory bulb. Human ortholog(s) of this gene implicated in hemolytic anemia. Orthologous to human PGK1 (phosphoglycerate kinase 1).
Genome Resources: Alliance (1),  Gene:406696 (1),  Ensembl(GRCz11):ENSDARG00000054191 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-pgk1
1
MO1-pgk1 N/A 1
DISEASE ASSOCIATED WITH pgk1 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Phosphoglycerate kinase 1 deficiency 300653
DISEASE ASSOCIATED WITH pgk1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process response to hypoxia (more)
Cellular Component cytosol (more)
Molecular Function ATP binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pgk1-201 (1)    Ensembl 1945
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pgk1 No data available
MARKER RELATIONSHIPS
pgk1 Contained in: [BAC] DKEY-13F9 (1) (order this)
pgk1 Contains: [SNP] rs3729129 (1)
pgk1 Encodes: [EST] fd59b07 (1), fj36g06 (1)
[cDNA] MGC:56252 (1), MGC:77899 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213387 (1) 1922 nt
Genomic GenBank:BX842703 (1) 208780 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1QXV8 (1) 417 aa
Sequence Information (all 20)
ORTHOLOGY for pgk1 ( Chr: 21 )
CITATIONS (42)