ZFIN ID: ZDB-GENE-040426-2675
Gene Name: phosphatidylinositol 4-kinase type 2 alpha
Gene Symbol: pi4k2a    Nomenclature History

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Previous Names: pi4kii (1), PI4KII-alpha (1), wu:fc84f05, zgc:63646

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have 1-phosphatidylinositol 4-kinase activity; AP-3 adaptor complex binding activity; and ATP binding activity. Predicted to be involved in Golgi organization; endosome organization; and phosphatidylinositol metabolic process. Predicted to colocalize with BLOC-1 complex. Orthologous to human PI4K2A (phosphatidylinositol 4-kinase type 2 alpha).
Genome Resources: Alliance (1),  Gene:406667 (1),  Ensembl(GRCz11):ENSDARG00000033666 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63646]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021319Tg Transgenic Insertion Unknown Unknown DNA
sa8708 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31238 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38300 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pi4k2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pi4k2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphatidylinositol biosynthetic process (more)
    Cellular Component COLOCALIZES_WITH   BLOC-1 complex (more)
    Molecular Function 1-phosphatidylinositol 4-kinase activity (more)
    GO Terms (all 30)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pi4k2a-201 (1)    Ensembl 3822
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pi4k2a No data available
    MARKER RELATIONSHIPS
    pi4k2a Contained in: [BAC] CH211-197K17 (1), CH211-202H22 (1)
    pi4k2a Encodes: [EST] fc84f05 (1)
    [cDNA] MGC:63646 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213358 (1) 3958 nt
    Genomic GenBank:BX119918 (1) 141342 nt
    Select Tool
    Polypeptide UniProtKB:Q6PE18 (1) 447 aa
    Sequence Information (all 16)
    ORTHOLOGY for pi4k2a ( Chr: 1 )
    CITATIONS (35)