Gene

gab1

ID
ZDB-GENE-040426-2674
Name
GRB2-associated binding protein 1
Symbol
gab1 Nomenclature History
Previous Names
  • fb11b01
  • fc66d01
  • wu:fb11b01
  • wu:fc66d01
  • zgc:56412 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Involved in epiboly. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 26. Is expressed in brain and inner ear. Orthologous to human GAB1 (GRB2 associated binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Yousaf et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gab1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 26 Alliance ?Deafness, autosomal recessive 26 605428
Associated With gab1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length PH-like domain superfamily Pleckstrin homology domain
UniProtKB:Q7ZWG0 405
UniProtKB:F6NTT0 712
UniProtKB:F1Q7S5 740
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations