ZFIN ID: ZDB-GENE-040426-2650
Gene Name: cathepsin Ba
Gene Symbol: ctsba    Nomenclature History

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Previous Names: ctsb, id:ibd1201, wu:fa13g05, wu:fb34e12, zgc:55862, zgc:65809, zgc:77181 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity. Involved in dorsal/ventral pattern formation; fin regeneration; and morphogenesis of an epithelium. Predicted to localize to extracellular space and lysosome. Is expressed in several structures, including blastoderm cell; endocrine system; macrophage; midbrain hindbrain boundary; and yolk. Human ortholog(s) of this gene implicated in diabetes mellitus. Orthologous to human CTSB (cathepsin B).
Genome Resources: Alliance (1),  Gene:406645 (1),  Ensembl(GRCz11):ENSDARG00000055120 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
p24bdth Unknown Unknown Unknown ENU
DISEASE ASSOCIATED WITH ctsba HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Keratolytic winter erythema 148370
DISEASE ASSOCIATED WITH ctsba VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process convergent extension (more)
Cellular Component extracellular space (more)
Molecular Function cysteine-type endopeptidase activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ctsba-201 (1)    Ensembl 1429
ctsba-208 (1)    Ensembl 920
ncRNA ctsba-002 (1)    Ensembl 777
ctsba-003 (1)    Ensembl 939
ctsba-004 (1)    Ensembl 778
ctsba-005 (1)    Ensembl 796
ctsba-007 (1)    Ensembl 562
ctsba-008 (1)    Ensembl 619
ctsba-009 (1)    Ensembl 848
ctsba-010 (1)    Ensembl 563
Browsers: UCSCEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ctsba No data available
MARKER RELATIONSHIPS
ctsba Contained in: [BAC] CH73-21C1 (1)
ctsba Encodes: [EST] fa13g05 (1), fb34e12 (1), ibd1201 (1)
[cDNA] MGC:55862 (1), MGC:65809 (1), MGC:77181
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213336 (1) 1444 nt
Genomic GenBank:CU019637 (1) 35269 nt
Select Tool
Polypeptide UniProtKB:Q6PH75 (1) 330 aa
Sequence Information (all 26)
ORTHOLOGY for ctsba ( Chr: 17 )
CITATIONS (44)