ZFIN ID: ZDB-GENE-040426-2590
Gene Name: family with sequence similarity 49 member Bb
Gene Symbol: fam49bb    Nomenclature History

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Previous Names: si:dkeyp-105g12.2, zgc:76981 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to be involved in positive regulation of T cell activation. Is expressed in brain; corpuscles of Stannius; pancreas primordium; and pronephric duct. Orthologous to human CYRIB (CYFIP related Rac1 interactor B).
Genome Resources: Alliance (1),  Gene:404610 (1),  Ensembl(GRCz11):ENSDARG00000045417 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6147 Point Mutation Unknown Premature Stop ENU
sa44097 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu499Gt Transgenic Insertion Unknown Unknown DNA
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fam49bb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fam49bb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of T cell activation (more)
    Cellular Component cellular_component (more)
    Molecular Function molecular_function (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fam49bb-203 (1)    Ensembl 1211
    fam49bb-204 (1)    Ensembl 262
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fam49bb No data available
    MARKER RELATIONSHIPS
    fam49bb Contained in: [BAC] DKEY-37O8 (1) (order this), DKEYP-105G12 (1)
    fam49bb Encodes: [EST] IMAGE:7148971 (1)
    [cDNA] MGC:76981 (1), MGC:173919 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_207078 (1) 1347 nt
    Genomic GenBank:AL840641 (1) 177428 nt
    Select Tool
    Polypeptide UniProtKB:F1R243 (1) 383 aa
    Sequence Information (all 21)
    ORTHOLOGY for fam49bb ( Chr: 24 )
    CITATIONS (21)