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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2581
Gene Name: enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
Gene Symbol: ehhadh    Nomenclature History

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Previous Names: l-pbe (1), zgc:77526

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have 3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to the peroxisome. Human ortholog(s) of this gene implicated in Fanconi syndrome. Is expressed in male organism. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase).
Genome Resources: Alliance (1),  Gene:100000859 (1),  Ensembl(GRCz11):ENSDARG00000070029 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77526]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2485 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41367 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-ehhadh
    2
    CRISPR2-ehhadh
    2
    CRISPR3-ehhadh
    2
    CRISPR4-ehhadh
    2
    CRISPR5-ehhadh
    2
    CRISPR6-ehhadh
    2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ehhadh HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Fanconi syndrome Alliance ?Fanconi renotubular syndrome 3 615605
    DISEASE ASSOCIATED WITH ehhadh VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid beta-oxidation (more)
    Cellular Component peroxisome (more)
    Molecular Function 3-hydroxyacyl-CoA dehydrogenase activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ehhadh-201 (1)    Ensembl 2480
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ehhadh No data available
    MARKER RELATIONSHIPS
    ehhadh Contained in: [BAC] DKEYP-30D5 (1)
    ehhadh Encodes: [cDNA] MGC:77526 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_207068 (1) 2303 bp
    Genomic GenBank:CR936497 (1) 162054 bp
    Select Tool
    Polypeptide UniProtKB:Q6NYL3 (1) 718 aa
    Sequence Clusters UniGene:80045 (1)
    Sequence Information (all 15)
    ORTHOLOGY for ehhadh ( Chr: 9 )
    CITATIONS (36)