Gene

ehhadh

ID
ZDB-GENE-040426-2581
Name
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
Symbol
ehhadh Nomenclature History
Previous Names
  • l-pbe (1)
  • zgc:77526
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to peroxisome. Is expressed in male organism. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 3. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ehhadh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fanconi renotubular syndrome 3 Alliance ?Fanconi renotubular syndrome 3 615605
Associated With ehhadh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site
Conserved_site IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Domain IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
Domain IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
Family IPR001753 Enoyl-CoA hydratase/isomerase
Homologous_superfamily IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Homologous_superfamily IPR029045 ClpP/crotonase-like domain superfamily
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 3-hydroxyacyl-CoA dehydrogenase, conserved site 3-hydroxyacyl-CoA dehydrogenase, C-terminal 3-hydroxyacyl-CoA dehydrogenase, NAD binding 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily ClpP/crotonase-like domain superfamily Enoyl-CoA hydratase/isomerase Enoyl-CoA hydratase/isomerase, conserved site NAD(P)-binding domain superfamily
UniProtKB:Q6NYL3 718
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations