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Gene

ehhadh

ID
ZDB-GENE-040426-2581
Name
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
Symbol
ehhadh Nomenclature History
Previous Names
  • l-pbe (1)
  • zgc:77526
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; and long-chain-3-hydroxyacyl-CoA dehydrogenase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to act upstream of or within fatty acid metabolic process. Predicted to be active in peroxisome. Is expressed in male organism. Human ortholog(s) of this gene implicated in Fanconi renotubular syndrome 3. Orthologous to human EHHADH (enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ehhadh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fanconi renotubular syndrome 3 Alliance ?Fanconi renotubular syndrome 3 615605
Associated With ehhadh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site
Conserved_site IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Domain IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal
Domain IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
Family IPR001753 Enoyl-CoA hydratase/isomerase
Homologous_superfamily IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily
Homologous_superfamily IPR029045 ClpP/crotonase-like domain superfamily
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 3-hydroxyacyl-CoA dehydrogenase, conserved site 3-hydroxyacyl-CoA dehydrogenase, C-terminal 3-hydroxyacyl-CoA dehydrogenase, NAD binding 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily ClpP/crotonase-like domain superfamily Enoyl-CoA hydratase/isomerase Enoyl-CoA hydratase/isomerase, conserved site NAD(P)-binding domain superfamily
UniProtKB:Q6NYL3 718
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations