Gene

irf2bp2b

ID
ZDB-GENE-040426-2574
Name
interferon regulatory factor 2 binding protein 2b
Symbol
irf2bp2b Nomenclature History
Previous Names
  • irf2bp2
  • wu:fa12b04
  • wu:fb73g01
  • zgc:63864
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have transcription corepressor activity and ubiquitin protein ligase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including immature eye; musculature system; nervous system; notochord; and pronephric duct. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human IRF2BP2 (interferon regulatory factor 2 binding protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Wang et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With irf2bp2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
common variable immunodeficiency 14 Alliance ?Immunodeficiency, common variable, 14 617765
Associated With irf2bp2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022750 Interferon regulatory factor 2-binding protein 1 & 2, zinc finger
Homologous_superfamily IPR044882 Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily
Domain Details Per Protein
Protein Length Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily Interferon regulatory factor 2-binding protein 1 & 2, zinc finger
UniProtKB:A0A0R4ITA7 501
UniProtKB:Q7T2G1 501
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations