ZFIN ID: ZDB-GENE-040426-2556
Gene Name: peroxiredoxin like 2B
Gene Symbol: prxl2b    Nomenclature History

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Previous Names: prxl2 (1), fam213b, sb:cb782, selu3 (1), wu:fc33a02, zgc:85644

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have antioxidant activity and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in oxidation-reduction process and prostaglandin biosynthetic process. Predicted to localize to the cytosol. Is expressed in gut and pronephric duct. Orthologous to human PRXL2B (peroxiredoxin like 2B).
Genome Resources: Alliance (1),  Gene:406605 (1),  Ensembl(GRCz11):ENSDARG00000029795 (2)
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 4 figures (8 images) from Thisse et al., 2001 [cb782]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13891 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21971 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH prxl2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH prxl2b VIA EXPERIMENTAL MODELS No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
    Family IPR032801 Peroxiredoxin-like 2A/B/C
    Homologous_superfamily IPR036249 Thioredoxin-like superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fam213b-202 (1)    Ensembl 1461
    fam213b-203 (1)    Ensembl 658
    fam213b-204 (1)    Ensembl 708
    ncRNA fam213b-002 (1)    Ensembl 877
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prxl2b No data available
    MARKER RELATIONSHIPS
    prxl2b Contained in: [BAC] CH211-222L21 (1)
    prxl2b Encodes: [EST] cb782 (1) (order this), fc33a02 (1)
    [cDNA] MGC:85644 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213313 (1) 1384 nt
    Genomic GenBank:AL954137 (1) 222162 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QSW9 (1) 201 aa
    Sequence Information (all 15)
    ORTHOLOGY for prxl2b ( Chr: 11 )
    CITATIONS (29)