ZFIN ID: ZDB-GENE-040426-2547
Gene Name: leucine rich repeat containing 59
Gene Symbol: lrrc59    Nomenclature History

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Previous Name: zgc:85752 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to localize to several cellular components, including endoplasmic reticulum; endoplasmic reticulum membrane; and nuclear envelope. Is expressed in several structures, including axis; hatching gland; notochord; otic vesicle; and polster. Orthologous to human LRRC59 (leucine rich repeat containing 59).
Genome Resources: Alliance (1),  Gene:405868 (1),  Ensembl(GRCz11):ENSDARG00000071426 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [IMAGE:6908892]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31886 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH lrrc59 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lrrc59 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of Ras protein signal transduction (more)
    Cellular Component endoplasmic reticulum (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lrrc59-201 (1)    Ensembl 1415
    ncRNA lrrc59-002 (1)    Ensembl 835
    lrrc59-003 (1)    Ensembl 800
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lrrc59 No data available
    MARKER RELATIONSHIPS
    lrrc59 Contained in: [BAC] DKEY-49C17 (1) (order this)
    lrrc59 Encodes: [EST] IMAGE:6908892 (1)
    [cDNA] MGC:85752 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212932 (1) 1397 nt
    Genomic GenBank:CR450698 (1) 155402 nt
    Select Tool
    Polypeptide UniProtKB:F1R8Q3 (1) 314 aa
    Sequence Information (all 12)
    ORTHOLOGY for lrrc59 ( Chr: 12 )
    CITATIONS (24)