ZFIN ID: ZDB-GENE-040426-2532
Gene Name: phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Gene Symbol: pik3cg    Nomenclature History

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Previous Names: wu:fb15d07, zgc:77033

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have 1-phosphatidylinositol-3-kinase activity and 1-phosphatidylinositol-4-phosphate 3-kinase activity. Involved in neutrophil chemotaxis. Predicted to localize to cytoplasm; phosphatidylinositol 3-kinase complex, class IB; and plasma membrane. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma).
Genome Resources: Alliance (1),  Gene:406598 (1),  Ensembl(GRCz11):ENSDARG00000017757 (2)
GENE EXPRESSION
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15462 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40205 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um124 Indel Unknown Unknown ZINC_FINGER_NUCLEASE
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pik3cg N/A 1
    MO2-pik3cg N/A 3
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pik3cg HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pik3cg VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neutrophil chemotaxis (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pik3cg-201 (1)    Ensembl 4762
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pik3cg No data available
    MARKER RELATIONSHIPS
    pik3cg Contained in: [BAC] CH73-134B5 (1)
    pik3cg Encodes: [EST] fb15d07 (1)
    [cDNA] MGC:64029 (1), MGC:77033 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213306 (1) 4770 nt
    Genomic GenBank:CU928083 (1) 107444 nt
    Select Tool
    Polypeptide UniProtKB:F1QVE6 (1) 1098 aa
    Sequence Information (all 19)
    ORTHOLOGY for pik3cg ( Chr: 4 )
    CITATIONS (26)