Gene
socs3b
- ID
- ZDB-GENE-040426-2528
- Name
- suppressor of cytokine signaling 3b
- Symbol
- socs3b Nomenclature History
- Previous Names
-
- zgc:77038
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within brain development. Predicted to be part of phosphatidylinositol 3-kinase complex. Is expressed in eye; heart; lateral line ganglion; and segmental plate. Human ortholog(s) of this gene implicated in atopic dermatitis 4. Orthologous to human SOCS3 (suppressor of cytokine signaling 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 14 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:77038 (9 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | SH2 domain | SH2 domain superfamily | SOCS3, SH2 domain | SOCS box domain | SOCS box-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q6NYJ2
|
210 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
socs3b-201
(1)
|
2155 nt | |
| mRNA |
socs3b-202
(1)
|
874 nt |
Interactions and Pathways
No data available
Plasmids
No data available