Gene

utp4

ID

ZDB-GENE-040426-2466

Name

UTP4 small subunit processome component

Symbol

utp4 Nomenclature History

Previous Names

cirh1a (1)
wu:fi09g10
wu:fi37c02
zgc:77199

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Description

Involved in hepaticobiliary system process. Predicted to localize to 90S preribosome; small-subunit processome; and t-UTP complex. Human ortholog(s) of this gene implicated in cholestasis and primary biliary cirrhosis. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; nervous system; and segmental plate. Orthologous to human UTP4 (UTP4 small subunit processome component).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6903903 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Wilkins et al., 2013
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With utp4 Human Ortholog

No data available

Associated With utp4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat