ZFIN ID: ZDB-GENE-040426-2405
Gene Name: eukaryotic translation initiation factor 5A2
Gene Symbol: eif5a2    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: wu:fb05b06, wu:fc23f04, wu:fc61c10, zgc:55504 (1), zgc:77429

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have translation elongation factor activity. Predicted to be involved in positive regulation of translational elongation. Orthologous to several human genes including EIF5A2 (eukaryotic translation initiation factor 5A2).
Genome Resources: Alliance (1),  Gene:406546 (1),  Ensembl(GRCz11):ENSDARG00000056186 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:55504]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa19765 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eif5a2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH eif5a2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of translational elongation (more)
    Molecular Function ribosome binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001884 Translation elongation factor IF5A-like
    Homologous_superfamily IPR008991 Translation protein SH3-like domain superfamily
    Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
    Homologous_superfamily IPR014722 Ribosomal protein L2, domain 2
    PTM IPR019769 Translation elongation factor, IF5A, hypusine site
    Domain IPR020189 Translation elongation factor, IF5A C-terminal
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA eif5a2-201 (1)    Ensembl 2793
    eif5a2-203 (1)    Ensembl 814
    eif5a2-204 (1)    Ensembl 626
    eif5a2-205 (1)    Ensembl 830
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM eif5a2 No data available
    MARKER RELATIONSHIPS
    eif5a2 Contained in: [BAC] DKEY-153N9 (1) (order this)
    eif5a2 Contains: [STS] chunp30279
    eif5a2 Encodes: [EST] fb05b06 (1), fc23f04 (1), fc61c10 (1)
    [cDNA] MGC:55504, MGC:77429 (1), MGC:192081 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213262 (1) 2432 bp
    Genomic GenBank:CR392026 (1) 191490 bp
    Select Tool
    Polypeptide UniProtKB:Q7ZUP4 (1) 155 aa
    Sequence Information (all 22)
    ORTHOLOGY for eif5a2 ( Chr: 2 )
    CITATIONS (27)