ZFIN ID: ZDB-GENE-040426-2395
Gene Name: ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
Gene Symbol: arih1l    Nomenclature History

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Previous Names: wu:fc12f04, zgc:85905

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have ubiquitin conjugating enzyme binding activity; ubiquitin protein ligase activity; and zinc ion binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to localize to the cytoplasm and ubiquitin ligase complex. Orthologous to human ARIH1 (ariadne RBR E3 ubiquitin protein ligase 1).
Genome Resources: Alliance (1),  Gene:405859 (1),  Ensembl(GRCz11):ENSDARG00000036870 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85905]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7060 Point Mutation Unknown Splice Site ENU
sa18366 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH arih1l HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arih1l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein ubiquitination (more)
    Cellular Component cytoplasm (more)
    Molecular Function ubiquitin-protein transferase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR002867 IBR domain
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Family IPR031127 E3 ubiquitin ligase RBR family
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arih1l-201 (1)    Ensembl 4758
    ncRNA arih1l-002 (1)    Ensembl 528
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arih1l No data available
    MARKER RELATIONSHIPS
    arih1l Contained in: [BAC] CH211-132L2 (1)
    arih1l Encodes: [EST] fc12f04
    [cDNA] MGC:85905 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212923 (1) 1803 bp
    Genomic GenBank:CT030046 (1) 174189 bp
    Select Tool
    Polypeptide UniProtKB:Q6NW85 (1) 533 aa
    Sequence Information (all 11)
    ORTHOLOGY for arih1l ( Chr: 7 )
    CITATIONS (19)