ZFIN ID: ZDB-GENE-040426-2385
Gene Name: casein kinase 1, delta b
Gene Symbol: csnk1db    Nomenclature History

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Previous Names: csnk1d, wu:fb69b03, wu:fj97a05, zgc:77627

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in several processes, including non-motile cilium assembly; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein phosphorylation. Predicted to localize to the cytoplasm; nucleus; and spindle microtubule. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 2. Is expressed in several structures, including axis; brain; notochord; presumptive neural retina; and yolk syncytial layer. Orthologous to human CSNK1D (casein kinase 1 delta).
Genome Resources: Alliance (1),  Gene:406533 (1),  Ensembl(GRCz11):ENSDARG00000006125 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa35337 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH csnk1db HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    advanced sleep phase syndrome 2 Alliance Advanced sleep-phase syndrome, familial, 2 615224
    DISEASE ASSOCIATED WITH csnk1db VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000719 Protein kinase domain
    Active_site IPR008271 Serine/threonine-protein kinase, active site
    Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
    Binding_site IPR017441 Protein kinase, ATP binding site
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA csnk1db-201 (1)    Ensembl 3081
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM csnk1db No data available
    MARKER RELATIONSHIPS
    csnk1db Contained in: [BAC] DKEY-105J12 (1) (order this)
    csnk1db Encodes: [EST] fb69b03 (1), fj97a05 (1), fc48c05 (1)
    [cDNA] MGC:77627 (1), MGC:113966 (1), MGC:192649 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213250 (1) 3093 bp
    Genomic GenBank:CR932358 (1) 138570 bp
    Select Tool
    Polypeptide UniProtKB:B2GSL2 (1) 409 aa
    Sequence Information (all 25)
    ORTHOLOGY for csnk1db ( Chr: 12 )
    CITATIONS (30)