Gene

atf4a

ID
ZDB-GENE-040426-2340
Name
activating transcription factor 4a
Symbol
atf4a Nomenclature History
Previous Names
  • atf4
  • atf4b1
  • wu:fj01c08 (1)
  • wu:fk30b04
  • zgc:85951
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding protein binding activity; and protein heterodimerization activity. Predicted to be involved in several processes, including HRI-mediated signaling; animal organ development; and regulation of transcription by RNA polymerase II. Predicted to localize to ATF1-ATF4 transcription factor complex and ATF4-CREB1 transcription factor complex. Is expressed in eye; head; hindbrain; liver; and trunk. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human ATF4 (activating transcription factor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 24 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atf4a Human Ortholog
No data available
Associated With atf4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Homologous_superfamily IPR046347 Basic-leucine zipper domain superfamily
Domain Details Per Protein
Protein Length Basic-leucine zipper domain Basic-leucine zipper domain superfamily
UniProtKB:Q6NW59 339
UniProtKB:A0A8M2BJE3 338
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations