ZFIN ID: ZDB-GENE-040426-2338
Gene Name: sprouty-related, EVH1 domain containing 1
Gene Symbol: spred1

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Previous Names: fb14c08, fj51c03, wu:fb14c08 (1), wu:fj51c03 (1), zgc:85707 (1)

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85707]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  unspecified, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6494 Point Mutation Unknown Premature Stop ENU
sa15659 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32178 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-spred1 (1), MO2-spred1 (1), MO3-spred1 (1)
    PHENOTYPE
    Data: Fig. S9 from Fish et al., 2008
    Observed in: blood circulation, cranial vasculature, heart
    DISEASE ASSOCIATED WITH spred1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Legius syndrome 611431
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel morphogenesis (more)
    Cellular Component membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000697 (1)
  • InterPro:IPR007875 (1)
  • InterPro:IPR011993 (1)
  • InterPro:IPR023337 (1)
  • PROSITE:PS50229 (1)
  • PROSITE:PS51227 (1)
  • PROSITE:PS51488 (1)
  • Pfam:PF00568 (1)
  • Pfam:PF05210 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA spred1-001 (1) 3432
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM spred1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    spred1Contained in: [BAC] CH73-275L12 (1) (order this), CH211-173A9 (1) (order this)
    spred1Encodes: [EST] fb14c08, fj51c03
    [cDNA] MGC:85707 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213232 (1) 3089bp
    Genomic GenBank:AL935141 (1) 136178bp
    Select Tool
    Polypeptide UniProtKB:F1R8L9 (1) 391aa
    Sequence Clusters UniGene:76703 (1)
    Sequence Information (all 15)
    OTHER spred1 GENE PAGES
  • Gene:406513 (1)
  • VEGA:OTTDARG00000035030 (1)
  • Ensembl(GRCz10):ENSDARG00000041449 (1)
  • ORTHOLOGY for spred1 (Chr: 17)
    Species Symbol Chromosome Accession # Evidence
    Human SPRED1 15
  • Gene:161742
  • OMIM:609291
  • HGNC:20249
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Spred1 2
  • MGI:2150016
  • Gene:114715
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (17)