ZFIN ID: ZDB-GENE-040426-2328
Gene Name: methyltransferase like 14
Gene Symbol: mettl14    Nomenclature History

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Previous Name: zgc:77296 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to contribute to mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity. Predicted to be involved in several processes, including forebrain radial glial cell differentiation; mRNA destabilization; and mRNA metabolic process. Predicted to localize to RNA N6-methyladenosine methyltransferase complex and nucleus. Orthologous to human METTL14 (methyltransferase like 14).
Genome Resources: Alliance (1),  Gene:404603 (1),  Ensembl(GRCz11):ENSDARG00000070278 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77296]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa12796 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko388b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-mettl14 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH mettl14 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH mettl14 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process forebrain radial glial cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA mettl14-201 (1)    Ensembl 1714
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mettl14 No data available
    MARKER RELATIONSHIPS
    mettl14 Contained in: [BAC] CH211-195F22 (1), CH211-201G8 (1)
    mettl14 Encodes: [cDNA] MGC:77296 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_207071 (1) 1730 nt
    Genomic GenBank:BX511083 211668 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6NZ22 (1) 455 aa
    Sequence Information (all 10)
    ORTHOLOGY for mettl14 ( Chr: 1 )
    CITATIONS (17)