Gene

gnl2

ID
ZDB-GENE-040426-2317
Name
guanine nucleotide binding protein-like 2 (nucleolar)
Symbol
gnl2 Nomenclature History
Previous Names
  • wu:fc15c12
  • zgc:65800 (1)
  • zgc:77319
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have GTP binding activity. Involved in several processes, including cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neural retina development; and regulation of exit from mitosis. Predicted to localize to nucleolus. Is expressed in several structures, including head; immature eye; midbrain; neural plate; and segmental plate. Orthologous to human GNL2 (G protein nucleolar 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnl2 Human Ortholog
No data available
Associated With gnl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006073 GTP binding domain
Domain IPR012971 Nucleolar GTP-binding protein 2, N-terminal domain
Domain IPR030378 Circularly permuted (CP)-type guanine nucleotide-binding (G) domain
Family IPR024929 Nucleolar GTP-binding protein 2
Homologous_superfamily IPR023179 GTP-binding protein, orthogonal bundle domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Circularly permuted (CP)-type guanine nucleotide-binding (G) domain GTP binding domain GTP-binding protein, orthogonal bundle domain superfamily Nucleolar GTP-binding protein 2 Nucleolar GTP-binding protein 2, N-terminal domain P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A8KC04 725
UniProtKB:Q7SZQ9 727
UniProtKB:A0A0R4IUN4 261
UniProtKB:A0A0R4IXF1 726
UniProtKB:Q7ZVQ6 517
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations