Gene

aga

ID
ZDB-GENE-040426-2311
Name
aspartylglucosaminidase
Symbol
aga Nomenclature History
Previous Names
  • zgc:77327
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity. Predicted to be involved in protein deglycosylation. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in aspartylglucosaminuria and lysosomal storage disease. Orthologous to human AGA (aspartylglucosaminidase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aga Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
aspartylglucosaminuria Alliance Aspartylglucosaminuria 208400
Associated With aga Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000246 Peptidase T2, asparaginase 2
Homologous_superfamily IPR029055 Nucleophile aminohydrolases, N-terminal
Domain Details Per Protein
Protein Length Nucleophile aminohydrolases, N-terminal Peptidase T2, asparaginase 2
UniProtKB:A0A8M9PZ91 215
UniProtKB:A8KC00 337
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations