Gene

six1b

ID
ZDB-GENE-040426-2308
Name
SIX homeobox 1b
Symbol
six1b Nomenclature History
Previous Names
  • six1 (1)
  • six1a (1)
  • zgc:77345 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including muscle organ development; nervous system development; and regulation of skeletal muscle cell proliferation. Predicted to localize to nucleus and transcription regulator complex. Is expressed in several structures, including cephalic musculature; ectoderm; muscle; peripheral nervous system; and pharyngeal arch. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Orthologous to human SIX1 (SIX homeobox 1).
Genome Resources
Note
None
Expression
All Expression Data
31 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 6 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With six1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant nonsyndromic deafness 23 Alliance Deafness, autosomal dominant 23 605192
branchiootic syndrome Alliance Branchiootic syndrome 3 608389
Associated With six1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:Q6NZ04 284
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations