ZFIN ID: ZDB-GENE-040426-2285
Gene Name: mannose-6-phosphate receptor (cation dependent)
Gene Symbol: m6pr    Nomenclature History

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Previous Names: CD-MPR (1), wu:fj81h11, zgc:77757

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Exhibits mannose binding activity and protein domain specific binding activity. Involved in protein targeting to lysosome. Localizes to trans-Golgi network. Is expressed in nervous system; presumptive neural retina; and somite. Orthologous to human M6PR (mannose-6-phosphate receptor, cation dependent).
Genome Resources: Alliance (1),  Gene:406486 (1),  Ensembl(GRCz11):ENSDARG00000018432 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:77757]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa42695 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH m6pr HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH m6pr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein targeting to lysosome (more)
    Cellular Component trans-Golgi network (more)
    Molecular Function mannose binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA m6pr-201 (1)    Ensembl 2429
    m6pr-202 (1)    Ensembl 898
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM m6pr No data available
    MARKER RELATIONSHIPS
    m6pr Contained in: [BAC] CH73-204P13 (1)
    m6pr Encodes: [EST] fj81h11 (1)
    [cDNA] MGC:77757 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213205 (1) 1979 nt
    Genomic GenBank:FP015958 (1) 97500 nt
    Select Tool
    Polypeptide UniProtKB:Q6P032 (1) 265 aa
    Sequence Information (all 14)
    ORTHOLOGY for m6pr ( Chr: 16 )
    CITATIONS (22)