ZFIN ID: ZDB-GENE-040426-2279
Gene Name: glycerophosphodiester phosphodiesterase domain containing 3a
Gene Symbol: gdpd3a    Nomenclature History

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Previous Names: gdpd3, wu:fl20d04, zgc:77781

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have lysophospholipase activity and phosphoric diester hydrolase activity. Involved in brain development. Predicted to localize to the endoplasmic reticulum membrane. Is expressed in brain; lens; and pronephric duct. Orthologous to human GDPD3 (glycerophosphodiester phosphodiesterase domain containing 3).
Genome Resources: Alliance (1),  Gene:406482 (1),  Ensembl(GRCz11):ENSDARG00000074466 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 7 figures (6 images) from Thisse et al., 2004 [IMAGE:7152344]
Wild-type Stages, Structures: Blastula:256-cell (2.5h-2.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa10838 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16999 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20018 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-gdpd3a N/A 2
    DISEASE ASSOCIATED WITH gdpd3a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gdpd3a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function phosphoric diester hydrolase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Homologous_superfamily IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily
    Domain IPR030395 Glycerophosphodiester phosphodiesterase domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gdpd3a-201 (1)    Ensembl 1577
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gdpd3a No data available
    MARKER RELATIONSHIPS
    gdpd3a Contained in: [BAC] CH73-33I10 (1)
    gdpd3a Encodes: [EST] fl20d04 (1), IMAGE:7152344 (1)
    [cDNA] MGC:77781 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213201 (1) 1310 bp
    Genomic GenBank:FP016144 (1) 105292 bp
    Select Tool
    Polypeptide UniProtKB:Q6P2T3 (1) 315 aa
    Sequence Information (all 11)
    ORTHOLOGY for gdpd3a ( Chr: 3 )
    CITATIONS (22)