ZFIN ID: ZDB-GENE-040426-2252
Gene Name: tumor necrosis factor receptor superfamily, member 1a
Gene Symbol: tnfrsf1a
Sequence Ontology ID : SO:0000704

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Previous Names: TNFR1 (1), TNF Receptor 1 (TR1) (1), wu:fj65b10, zgc:85914

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have tumor necrosis factor binding activity and tumor necrosis factor-activated receptor activity; involved in several processes, including defense response to bacterium, fin  ...
GENE EXPRESSION
All Expression Data: 11 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:85914]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb319 Insertion Unknown Unknown CRISPR
ihb320 Small Deletion Unknown Unknown CRISPR
sa8496 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15813 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tnfrsf1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant familial periodic fever Periodic fever, familial 142680
    {Multiple sclerosis, susceptibility to, 5} 614810
    DISEASE ASSOCIATED WITH tnfrsf1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of granuloma formation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function tumor necrosis factor-activated receptor activity (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000488 (1)
  • InterPro:IPR001368 (1)
  • InterPro:IPR011029 (1)
  • InterPro:IPR033994 (1)
  • InterPro:IPR033995 (1)
  • PROSITE:PS00652 (1)
  • PROSITE:PS50017 (1)
  • PROSITE:PS50050 (1)
  • Pfam:PF00020 (1)
  • Pfam:PF00531 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tnfrsf1a-001 (1) 2509
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tnfrsf1a No data available
    MARKER RELATIONSHIPS
    tnfrsf1aContained in: [BAC] CH211-215M13 (1) (order this)
    tnfrsf1aEncodes: [EST] fj65b10
    [cDNA] MGC:85914 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213190 (1) 2543bp
    Genomic GenBank:CR533575 (1) 115032bp
    Select Tool
    Polypeptide UniProtKB:F1QQS0 (1) 389aa
    Sequence Clusters UniGene:27758 (1)
    Sequence Information (all 11)
    OTHER tnfrsf1a GENE PAGES
  • Alliance (1)
  • Gene:406471 (1)
  • VEGA:OTTDARG00000022106 (1)
  • Ensembl(GRCz11):ENSDARG00000018569 (2)
  • ORTHOLOGY for tnfrsf1a (Chr: 16)
    CITATIONS (45)