ZFIN ID: ZDB-GENE-040426-2232
Gene Name: microtubule-associated protein 1 light chain 3 alpha
Gene Symbol: map1lc3a    Nomenclature History

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Previous Name: zgc:77094

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in autophagy of mitochondrion; cellular response to nitrogen starvation; and macroautophagy. Predicted to localize to autophagosome membrane and cytosol. Is expressed in forerunner cell group; nervous system; neural tube; and tail bud. Human ortholog(s) of this gene implicated in glioblastoma multiforme. Orthologous to human MAP1LC3A (microtubule associated protein 1 light chain 3 alpha).
Genome Resources: Alliance (1),  Gene:406466 (1),  Ensembl(GRCz11):ENSDARG00000033609 (2)
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 6 figures (9 images) from Thisse et al., 2004 [MGC:77094]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH map1lc3a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH map1lc3a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process autophagy (more)
Cellular Component autophagosome (more)
Molecular Function microtubule binding (more)
GO Terms (all 12)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA map1lc3a-201 (1)    Ensembl 1511
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM map1lc3a No data available
MARKER RELATIONSHIPS
map1lc3a Contained in: [BAC] DKEY-57N24 (1) (order this)
map1lc3a Encodes: [cDNA] MGC:77094 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_214739 (1) 1509 nt
Genomic GenBank:CU467888 (1) 168058 nt
Select Tool
Polypeptide UniProtKB:Q6NX90 (1) 121 aa
Sequence Information (all 11)
ORTHOLOGY for map1lc3a ( Chr: 11 )
CITATIONS (21)