ZFIN ID: ZDB-GENE-040426-2209
Gene Name: epithelial cell adhesion molecule
Gene Symbol: epcam
Sequence Ontology ID : SO:0000704

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Previous Names: pan-epithelial glycoprotein (1), sb:cb6, tacstd, wu:fj17g02, zgc:110304 (1), zgc:77119

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 20 figures from 14 publications
Directly Submitted Expression Data: 6 figures (24 images) from Thisse et al., 2001 [cb6]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  anterior lateral line placode, anterior lateral line primordium, anterior lateral line system, apical ectodermal ridge pectoral fin bud (all 30) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2151Tg Transgenic Insertion Unknown Unknown DNA
hi2836Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22225 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-epcam (1), MO2-epcam (1), MO3-epcam (1)
    PHENOTYPE
    Data: 17 figures from 5 publications
    Observed in: apical junction assembly, apoptotic process, cell proliferation, epiboly involved in gastrulation with mouth forming second (all 15) expand
    DISEASE ASSOCIATED WITH epcam HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital diarrhea 5 with tufting enteropathy Diarrhea 5, with tufting enteropathy, congenital 613217
    Lynch syndrome Colorectal cancer, hereditary nonpolyposis, type 8 613244
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell-cell adhesion (more)
    Cellular Component basolateral plasma membrane (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000716 (1)
  • PROSITE:PS00484 (1)
  • PROSITE:PS51162 (1)
  • Pfam:PF00086 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA epcam-001 (1) 1377
    ncRNA epcam-002 (1) 520
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM epcam No data available
    MARKER RELATIONSHIPS
    epcamContained in: [BAC] CH73-105B23 (1) (order this)
    epcamContains: [SNP] rs3728535 (1), rs3728536 (1)
    epcamEncodes: [EST] cb6 (1) (order this), fj17g02
    [cDNA] MGC:77119 (1) (order this), MGC:110304 (1) (order this)
    epcamHas Artifact: [EST] fb11f01
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001017593 (1) 1297bp
    Genomic GenBank:CU570977 (1) 114114bp
    Select Tool
    Polypeptide UniProtKB:B8JM11 (1) 303aa
    Sequence Clusters UniGene:39071 (1)
    Sequence Information (all 22)
    OTHER epcam GENE PAGES
  • Alliance (1)
  • Gene:406454 (1)
  • VEGA:OTTDARG00000029417 (1)
  • Ensembl(GRCz10):ENSDARG00000040534 (1)
  • ORTHOLOGY for epcam (Chr: 13)
    CITATIONS (48)