ZFIN ID: ZDB-GENE-040426-2185
Gene Name: tropomyosin 4a
Gene Symbol: tpm4a
Sequence Ontology ID : SO:0000704

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Previous Names: TPM4-1 (1), tpm4, wu:fb06e07, zgc:103436, zgc:63909

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have actin filament binding activity; involved in cardiac muscle contraction and cardiac myofibril assembly; predicted to localize to the actin filament; orthologous to human TPM4  ...
GENE EXPRESSION
All Expression Data: 18 figures from 8 publications
Directly Submitted Expression Data: 7 figures (17 images) from Thisse et al., 2004 [MGC:103436]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ct31aGt Transgenic Insertion Unknown Unknown DNA
sa11492 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf152Gt Transgenic Insertion Unknown Unknown DNA
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 4 figures from 3 publications
    Observed in:
    DISEASE ASSOCIATED WITH tpm4a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tpm4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cardiac muscle contraction (more)
    Cellular Component actin filament (more)
    Molecular Function actin filament binding (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000533 (1)
  • PROSITE:PS00326 (1)
  • Pfam:PF00261 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tpm4a-204 (1) 743
    tpm4a-205 (1) 1261
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tpm4a No data available
    MARKER RELATIONSHIPS
    tpm4aContained in: [BAC] RP71-69P9 (1) (order this)
    tpm4aEncodes: [EST] fb06e07 (1)
    [cDNA] MGC:63909 (1) (order this), MGC:103436 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213158 (1) 1804bp
    Genomic GenBank:BX322595 (1) 147460bp
    Select Tool
    Polypeptide UniProtKB:F1QKG7 (1) 284aa
    Sequence Clusters UniGene:76054 (1)
    Sequence Information (all 30)
    OTHER tpm4a GENE PAGES
  • Alliance (1)
  • Gene:406437 (1)
  • VEGA:OTTDARG00000009980 (1)
  • Ensembl(GRCz11):ENSDARG00000023963 (2)
  • ORTHOLOGY for tpm4a (Chr: 22)
    CITATIONS (38)