Gene

slc22a2

ID
ZDB-GENE-040426-2167
Name
solute carrier family 22 member 2
Symbol
slc22a2 Nomenclature History
Previous Names
  • oct1 (1)
  • wu:fc01b11
  • zgc:64076 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Exhibits transmembrane transporter activity. Involved in determination of heart left/right asymmetry. Localizes to integral component of plasma membrane. Is expressed in several structures, including eye; heart; liver; pleuroperitoneal region; and skeletal muscle. Human ortholog(s) of this gene implicated in acute kidney failure. Orthologous to several human genes including SLC22A2 (solute carrier family 22 member 2).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Shim et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc22a2 Human Ortholog
No data available
Associated With slc22a2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR005829 Sugar transporter, conserved site
Domain IPR020846 Major facilitator superfamily domain
Family IPR004749 Organic cation transport protein/SVOP
Family IPR005828 Major facilitator, sugar transporter-like
Homologous_superfamily IPR036259 MFS transporter superfamily
Domain Details Per Protein
Protein Length Major facilitator, sugar transporter-like Major facilitator superfamily domain MFS transporter superfamily Organic cation transport protein/SVOP Sugar transporter, conserved site
UniProtKB:Q5VSI5 562
UniProtKB:Q7T2C0 562
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations