ZFIN ID: ZDB-GENE-040426-2153
Gene Name: NADH:ubiquinone oxidoreductase core subunit S8a
Gene Symbol: ndufs8a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: ndufs8, wu:fb30b07, zgc:65835, zgc:77840 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to contribute to NADH dehydrogenase activity. Predicted to be involved in aerobic respiration; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Predicted to localize to mitochondrial respiratory chain complex I. Human ortholog(s) of this gene implicated in mitochondrial complex I deficiency. Orthologous to human NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8).
Genome Resources: Alliance (1),  Gene:406413 (1),  Ensembl(GRCz11):ENSDARG00000051986 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:65835]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa19550 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ndufs8a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Mitochondrial complex I deficiency, nuclear type 2 618222
    DISEASE ASSOCIATED WITH ndufs8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component membrane (more)
    Molecular Function 4 iron, 4 sulfur cluster binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ndufs8a-201 (1)    Ensembl 1575
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ndufs8a No data available
    MARKER RELATIONSHIPS
    ndufs8a Contained in: [BAC] DKEY-9I23 (1) (order this)
    ndufs8a Encodes: [EST] fb30b07 (1)
    [cDNA] MGC:65835 (1), MGC:77840
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_213139 (1) 1581 nt
    Genomic GenBank:BX901937 (1) 204746 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q6P0T0 (1) 210 aa
    Sequence Information (all 13)
    ORTHOLOGY for ndufs8a ( Chr: 1 )
    CITATIONS (27)