ZFIN ID: ZDB-GENE-040426-2150
Gene Name: ras homolog gene family, member Aa
Gene Symbol: rhoaa    Nomenclature History

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Previous Names: wu:fa66g04, wu:fb26g07, zgc:66058, zgc:85805 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have GTP binding activity and GTPase activity. Predicted to be involved in skeletal muscle satellite cell migration; stress fiber assembly; and wound healing, spreading of cells. Predicted to localize to cleavage furrow; cytoplasm; and dendritic spine. Human ortholog(s) of this gene implicated in breast carcinoma. Orthologous to human RHOA (ras homolog family member A).
Genome Resources: Alliance (1),  Gene:406411 (1),  Ensembl(GRCz11):ENSDARG00000026845 (2)
GENE EXPRESSION
All Expression Data: Fig. 4 from Salas-Vidal et al., 2005
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH rhoaa HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies, somatic mosaic 618727
DISEASE ASSOCIATED WITH rhoaa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process skeletal muscle satellite cell migration (more)
Cellular Component membrane (more)
Molecular Function GTPase activity (more)
GO Terms (all 22)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rhoaa-201 (1)    Ensembl 2194
rhoaa-203 (1)    Ensembl 807
ncRNA rhoaa-003 (1)    Ensembl 747
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM rhoaa No data available
MARKER RELATIONSHIPS
rhoaa Contained in: [BAC] DKEY-6N6 (1) (order this)
rhoaa Contains: [SNP] rs3728143 (1), rs3728144 (1)
rhoaa Encodes: [EST] fa66g04 (1), fb26g07 (1)
[cDNA] MGC:66058 (1), MGC:85805
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213137 (1) 2255 nt
Genomic GenBank:BX004884 (1) 225442 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q6NUX8 (1) 193 aa
Sequence Information (all 17)
ORTHOLOGY for rhoaa ( Chr: 8 )
CITATIONS (32)