Gene

ak3

ID
ZDB-GENE-040426-2142
Name
adenylate kinase 3
Symbol
ak3 Nomenclature History
Previous Names
  • ak3l1
  • id:ibd3034
  • sb:cb845
  • wu:fa02c11
  • wu:fc20h08
  • zgc:64135
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have adenylate kinase activity and nucleoside triphosphate adenylate kinase activity. Involved in myeloid cell development. Predicted to localize to mitochondrial matrix. Is expressed in blood; brain; notochord; tail bud; and yolk syncytial layer. Orthologous to human AK3 (adenylate kinase 3).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 2 from Gieger et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ak3 Human Ortholog
No data available
Associated With ak3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR033690 Adenylate kinase, conserved site
Domain IPR007862 Adenylate kinase, active site lid domain
Family IPR000850 Adenylate kinase/UMP-CMP kinase
Family IPR006259 Adenylate kinase subfamily
Family IPR028586 Adenylate kinase 3/4, mitochondrial
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036193 Adenylate kinase, active site lid domain superfamily
Domain Details Per Protein
Protein Length Adenylate kinase 3/4, mitochondrial Adenylate kinase, active site lid domain Adenylate kinase, active site lid domain superfamily Adenylate kinase, conserved site Adenylate kinase subfamily Adenylate kinase/UMP-CMP kinase P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F1R4S7 225
UniProtKB:Q7T333 214
UniProtKB:A8KBS5 214
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations