ZFIN ID: ZDB-GENE-040426-2114
Gene Name: glia maturation factor, beta
Gene Symbol: gmfb    Nomenclature History

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Previous Names: fc25b01, wu:fa97c03, wu:fc25b01, zgc:56451 (1), zgc:86831

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 13 Mapping Details/Browsers
Description: Predicted to have Arp2/3 complex binding activity; actin binding activity; and growth factor activity. Involved in reactive gliosis. Predicted to localize to actin cortical patch. Is expressed in head; hindbrain; and telencephalon. Orthologous to several human genes including GMFB (glia maturation factor beta).
Genome Resources: Alliance (1),  Gene:406384 (1),  Ensembl(GRCz11):ENSDARG00000028327 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6324 Point Mutation Unknown Splice Site ENU
zf2158 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-gmfb 1
MO1-gmfb N/A 1
PHENOTYPE
Data: Fig. 2 from Yin et al., 2018
Observed in:
DISEASE ASSOCIATED WITH gmfb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH gmfb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of Arp2/3 complex-mediated actin nucleation (more)
Molecular Function actin binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gmfb-201 (1)    Ensembl 2063
ncRNA gmfb-002 (1)    Ensembl 797
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gmfb No data available
MARKER RELATIONSHIPS
gmfb Contained in: [BAC] CH211-67F24 (1)
gmfb Encodes: [EST] fa97c03 (1), fc25b01 (1)
[cDNA] MGC:56451 (1), MGC:86831 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_213110 (1) 1928 nt
Genomic GenBank:BX927407 (1) 123739 nt
Select Tool
Polypeptide UniProtKB:Q7ZUD3 (1) 142 aa
Sequence Information (all 15)
ORTHOLOGY for gmfb ( Chr: 13 )
CITATIONS (24)