Gene

tead1a

ID
ZDB-GENE-040426-2101
Name
TEA domain family member 1a
Symbol
tead1a Nomenclature History
Previous Names
  • tead1
  • zgc:63696
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in embryonic organ development; hippo signaling; and regulation of transcription by RNA polymerase II. Predicted to localize to transcription regulator complex. Is expressed in nervous system; neural plate; and somite. Human ortholog(s) of this gene implicated in Sveinsson chorioretinal atrophy. Orthologous to human TEAD1 (TEA domain transcription factor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Fillatre et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tead1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sveinsson chorioretinal atrophy Alliance Sveinsson chorioretinal atrophy 108985
Associated With tead1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000818 TEA/ATTS domain
Domain IPR041086 YAP binding domain
Family IPR016361 Transcriptional enhancer factor, metazoa
Homologous_superfamily IPR038096 TEA/ATTS domain superfamily
Domain Details Per Protein
Protein Length TEA/ATTS domain TEA/ATTS domain superfamily Transcriptional enhancer factor, metazoa YAP binding domain
UniProtKB:Q7SXX3 393
UniProtKB:F1QLL3 422
UniProtKB:Q4V953 422
UniProtKB:E9QJ84 187
UniProtKB:A9JSZ6 420
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations